Animal-Free Safety Assessment (AFSA)

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First-of-its-kind AFSA Master Class in Animal-Free Safety Assessment for Cosmetics and Cosmetic Ingredients launched
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NEWS:
Global initiative launched to train scientists to safely test cosmetics, chemicals without painful and archaic animal experiments
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Imagine a world without animal testing… where the safety of chemicals, cosmetics, therapeutics and other products is assured using modern, human biology-based predictive tools. Making this world a reality is the goal of the AFSA Collaboration.

“I predict that 10 years from now, safety testing for newly developed drugs…will be largely carried out using human biochips…This approach…will mostly replace animal testing for drug toxicity and environmental sensing, giving results that are more accurate, at lower cost and with higher throughput.”

Francis Collins, MD, PhD
Director, U.S. National Institutes of Health 2016

The Animal-Free Safety Assessment (AFSA) Collaboration is a unique multi-sector partnership between non-profit, corporate, and philanthropic leaders working to advance acceptance and use of animal-free safety science as a gold standard across regulatory frameworks worldwide. Meet our members:

The Animal-Free Safety Assessment (AFSA) Collaboration brings together corporate and non-profit leaders who share the goal of accelerating a modern, species-relevant approach to safety assessment globally to better protect people and our planet, and hasten the replacement of animal testing. Meet our members:

Master Class Course Launch

A new online Master Class course to train scientists in testing cosmetics and chemicals without using animals is being hailed as a game-changer for cruelty-free testing worldwide.

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Publication: Last resort requirement under REACH

Europe’s failure to uphold the legal requirement of chemical testing on animals as a “last resort” exposed in new publication.

Publicaton

REGISTER: AFSA Master Class

Sign up for our Master Class in animal-free safety assessment of cosmetics and chemical ingredients, developed to to build confidence and capacity in the use of animal-free data in safety decision-making.

South Korea to include recombinant Factor C in the pharmacopoeia

The synthetic alternative for the Bacterial Endotoxin Test will be added in the Korean Pharmacopoeia. Another country is recognizing the sustainable choice to move away from horseshoe crabs derived reagent.

Landmark decision in India to drop obsolete test for vet vaccines

Indian Pharmacopoeia Commission commits to waive off the ‘Target Animal Batch Safety Test’ (TABST).

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Biologicals publication: Event series on animal testing alternative for vet vaccines

In collaboration with IABS, and veterinary industry association, HelathforAnimals, we hosted an event series on the implementation and regulatory acceptance of non-animal testing for veterinary vaccines’ batch release testing.

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REACHing for solutions: Essential revisions to the EU chemicals regulation to modernise safety assessment

Pereira M, Macmillan DS, Willett C, Seidle T.

Publisher’s website

Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients

Dent MP, Vaillancourt E, Thomas RS, Carmichael PL, Ouedraogo G, Kojima H, Barroso J, Ansell J, Barton-Maclaren TS, Bennekou SH, Boekelheide K, Ezendam J, Field J, Fitzpatrick S, Hatao M, Kreiling R, Lorencini M, Mahony C, Montemayor B, Mazaro-Costa R, Oliveira J, Rogiers V, Smegal D, Taalman R, Tokura Y, Verma R, Willett C, C. Yang

Publisher’s website

Systematic Review to Compare Chemical Hazard Predictions of the Zebrafish Embryotoxicity Test With Mammalian Prenatal Developmental Toxicity

Hoffmann S, Marigliani B, Akgün-Ölmez SG, Ireland D, Cruz R, Busquet F, Flick B, Lalu M, Ghandakly EC, de Vries RBM, Witters H, Wright RA, Ölmez M, Willett C, Hartung T, Stephens ML, Tsaioun KA

Publisher’s website

> View All

Animal-Free Safety Assessment (AFSA)

The Animal-Free Safety Assessment (AFSA) Collaboration is a unique multi-sector partnership between non-profit, corporate, and philanthropic leaders working to advance acceptance and use of animal-free safety science as a gold standard across regulatory frameworks worldwide. Meet our members:

Master Class Course Launch

Publication: Last resort requirement under REACH

REGISTER: AFSA Master Class

South Korea to include recombinant Factor C in the pharmacopoeia

Landmark decision in India to drop obsolete test for vet vaccines

Biologicals publication: Event series on animal testing alternative for vet vaccines

Latest Events

Webinar: Transition to non-animal based veterinary vaccine batch release testing. Policy and regulations theoretical aspects and case studies

Workshop on Animal Testing Alternatives for Biologicals

Virtual Workshop: Status of global implementation of MAT for biologicals. Product Specific Approaches and Regulatory Alignment

Introduction to recombinant Factor C and its future in India

The last resort requirement under REACH: From principle to practice

Transition to non-animal based vaccine batch release testing. Policy and regulations theoretical aspects and case studies.

REACHing for solutions: Essential revisions to the EU chemicals regulation to modernise safety assessment

Paving the way for application of next generation risk assessment to safety decision-making for cosmetic ingredients

Systematic Review to Compare Chemical Hazard Predictions of the Zebrafish Embryotoxicity Test With Mammalian Prenatal Developmental Toxicity